It could take me sometimes 2-3 weeks until it's time to refill. Not enough for penetration. Does anybody know what the real out-date is? I have been using trimix for about 4 years now.. The others 15-30 percent. Papaverine and phentolamine , (two of the 3 ingredients in Trimix), can be kept at room temperature and won't degrade that much. erections and one terrified man!) I am four months post robotic RP and am about to start Trimix injections. However, I've seen a few comments online saying that the one-month instruction is CYA by the pharmacies and the drugs actually last much longer. I have been on the pecker power shots for over 25 years. Urologist wanted to do removal surgery but I wasnt willing, so active surveillance for over 6 years now with 5 positive cores ( started with 2 ) out of 12 . Left at room temperature (22C), Trimix loses strength at 1% per day. Need help understanding labs. Now the urologist says I should do the seed implant. No incontenience but struggling with erections. He is scheduled for surgery on Dec. 2nd. my tw, I was advised today by my urologist that my ED is caused by tissue or nerve damage from my treatment which was 3 months of ADT (Firmagon), External Beam radiation plus brachytherapy completed July 2015. A long time! However, that information will still be included in details such as numbers of replies. Should I keep Tri-mix in the Refrigerator? At 2 weeks, I have noticed trimix is less effective. My urologist/surgeon prescribed Tri-mix Super Mayo at 3 months after RRP. Thinking about using injections but wanted some input before proceeding. 3. Prescribed Caverject Impulse alprostadil 10 micrograms injection. Would any incontinence be endurable? Left at room temperature (22C), Trimix loses strength at 1% per day. Together we are launching a campaign to shed light on this question: What is one unexpected way a cancer diagnosis has impacted your, I was diagnosed 2/5/16 at 54 years old . Basically, regardless of what pharmaceutical authorities tell you, the story is this : 1. Due to my traveling I cant take the Injections on the road with me. Today, I received the drugs and syringes from a compounding pharmacy. If the vial is stored in cotton wool soaked in isopropyl alcohol in a plastic zip bag, you shouldn't . Thankful I discovered this site to check out discussions that I would never have with my friends who have not had PC. After RP: Does anyone NOT suffer from ED. Refrigerated, Trimix loses strength at about 1% per week. I use Bi-mix -- I keep it in the freezer and just thaw it out long enough to draw a few syringes which I then keep in the refrigerator for use. What kind of sexual satisfaction would be possible? Since then the erections have not been 100%, 9/6/18: Diagnosed with prostate cancer after biopsy. After 20 weeks at 70F, a 37% loss was reported.. Testosterone Replacement, Low T, HCG, & Beyond, Penis Injections for Hard Erections: TRIMIX, Hormonal Approach for Postmenopausal Vulvovaginal Atrophy, Done with TRT and recovered within two weeks. When frozen, Trimix will last forever. It's not over just different. Some comments recommend storing the drugs in a freezer, but the instructions say not to freeze them once they've been opened. The good news is, my PSA has b, Hello. Testosterone (no ester) Suspension for Injection - Literature Review. i have had 4 biopsies during This time and psa has crept up to 8.6 . The short outdate is gift from the FDA (another stellar government agency). Again, I don't recommend room temperature for more than two days. There's hang on hunny while I fill my syringes and shoot up lol. 12Mg of Cypionate causing so many side effects? I am 16 weeks post robotic surgery for prostate removal, aged 64, happily married to my wife for 39 years. Daily Cialis didn't work. How long is trimix good for if kept refrigerated? I keep it refrigerated, used it successfully up to 18 months. Being a relatively young 56 in PC terms I'm concerned about the impact this will have on my life. If the vial is stored in cotton wool soaked in isopropyl alcohol in a plastic zip bag, you shouldn't have a problem. I have used refrigerated syringes of Trimix up to 6 months with good results. Still trying to get a second opinion. Room temperature exposure should be limited, and . 2004 May-Jun;8(3):231-5. , Human Chorionic Gonadotropin (HCG) Pregnyl, Why you should not use testosterone cream, Interview with Dr. Rich Sagall of NeedyMeds.org. His Father had it as well around the same age as him, so I am the youngest in the family to get it. Stage t1c. bimix shots work great but i was hoping for a return of erectile function. he was diagnosed at 55. Previously any male had 7 or 8 spontaneous, My husband is 52 years old and was diagnosed with stage one PC in June. We are a very sexually active couple. I'm in good health and fit. I freeze the vial that is not yet being used. wow im surprised it would be that fast. My urologist/surgeon prescribed Cialis 5mg daily beginning 2 weeks prior to surgery. Has any one had a similar experience and if so, what happened when you upped the does? I had to increase my dose, but I used it for 9 months! Even if previously you never used to 'pleasure yourself' it is important that you should start now! I prefill 20 syringes at a time. 2 of the votes were 40-60%. Hi - I was wondering if anyone out there has any experience with using a pump for ED after treatment for prostate cancer. Int J Pharm Compd. Dealing with this has been a bigger adventure than I would like. i am still dripping enough to have to wear a light pad and feel gross. 2. You are using an out of date browser. Here is what I do and works great. I have a question. I had three fears: Nobody knows my secret if I don't want them too. He has a Gleason score of a six. The ZERO - The End of Prostate Cancer Support Community connects patients, families, friends and caregivers to enhance the quality of life for all those affected by prostate cancer. But what Im wondering is if PC recovery has changed how men experience orgasm. Stress, Sleep, and Testosterone with Dr. Abe Morgentaler, BPC-157 to guard against Cipro induced tendon damage, Higher libido & more frequent erections from Ibuprofen & caffeine. It may not display this or other websites correctly. A. Leaning toward prostatectomy. The doctor said at last visit when we ask how long should he take can stop whenever you feel you are ok. Well how do you know when you have taken enough, things could still improve, but guess that is typical advice from some docs. At 34 weeks, the medication lost 25% and a 30% loss is seen after one full year at 41F. Gleason score 6 3+3 with a psa of 4.5 . After 7 weeks I needed to increase the dose by about 70%, but it worked well at that dosage. His brother is 14 years older and has stage 4 PC. Told these are undectable? So heres something Id like some feedback on. 3. Well I would like to say I use 20 of them in a few days but I am no spring chicken lol. During that time I have frozen the stuff, refrigerated it and left it at room temperature and have studied the results. After 3 months the first two fears are largely allayed. Kept cold(not frozen), I don't think it really goes bad. i have used the trimix up to 60 days after thawing. No problem with administering and no pain. Alprostadil lost 8% potency in five days at room temperature. Gleason score of 6. I then put those in a sun glass case along with my injector thingy. Maybe they dont know since all individuals are different in their re, Hi - I just came back from my Urologist after taking my first shot of Trimix. Surgeon said he spared the nerves but I'm wondering if that was really the case. So I am scared. JavaScript is disabled. 3. Hope that helps ease your concerns Roger. Dr. That was a couple months ago. Frozen at -20 deg C and -70 deg C, less than 5% loss of any of the drug componnets occurred in 6 months. Its even a bit weird talking with my wife on some of these issues. I'm disappointed as it only resulted in about a 60% erection. I have visited a. My preparation has these concentrations: PGE1 (8.3 mcg/ml); Phentolamine (0.8 mg/ml); Papaverine (22.5 mg/ml).Is that similar to what others are using?Thank. If there is a problem with long term room temperature storage, it is one of bacteriological contamination. with 10 units of Prostin(last October) but fast forward to this past June and having been prescribed Mirtazapine(Remeron)45mgs. Alprostadil lost 2% effectiveness under refrigeration after seven days. For a better experience, please enable JavaScript in your browser before proceeding. He gets rock hard when the, Well it's been 6 months since my RPS and first PSA .10 and second .05. also, i have no erectile response. 2. I was hoping to hear from others who can give me their tho, Most of us have a partner and sex was a thing that we always did together. No previous history of sexual dysfunction. All Rights Reserved. A beyond-use date of 6 months when stored frozen at -20 deg C and 1 month when stored refrigerated at 4 deg C is appropriate for batches of the injection that have passed sterility testing. I have been using the same vial for more than two years (I don't use a lot, or need it every time). After reading on this site about pumps, got one and the results are similar. Bi-mix lasts even longer. 1. Cialis had no affect what so ever. Now after a prostatectomy sex will never be the same again. Have my follow-up with my oncologist in a week or so. I guess I'll try .2 cc next week. I just sneak into the bathroom real quick, do my business and then get to business. My dad had very aggressive PC that spread to lymph-nodes. My husband has NEVER had ED. Sidenafil and Cialis don't provide a firm erection. Not just about the cancer but if the side effects. Currently on clomid. i take viagra often with no effect. 2. Today we are beginning a partnership with The Mighty, a publisher of stories by and about people facing medical challenges. I would also appreciate any female perspectives to this matter as well.My procedure was almost 3 years ago, and it was recommended that I have followup radiation. I have a Gleason 3+4 = 7 and looking at the options. The other is recommending going straight to injections.. If there is a problem with long term room temperature storage, it is one of bacteriological contamination. I was aghast to read instructions saying that the drugs are good for only a month! When I spoke with the pharmacy, they said the formula had not changed, just the required outdate. A couple of years ago I went overseas and stayed for 7 weeks in countries mostly without fridges in hotel rooms and therefore there was no refrigeration for most that time. I am recently married to, As I shared before the first time my husband did the injection at 10 in the office his erection was painful and lasted a little over 2 hours. I have been using Trimix for four and a half years and have had a total of 800 injections. I had 43 IMRT treatments that ended a year ago. Viagra didn't work. The effectiveness will be reduced approximately 10% per day so adjust your dose accordingly. I have kept trimix at room temperature for a week with no apparent loss of effectiveness. The good news is, after three PSA tests since the completion of my treatments, my PSA has remained below .1. One has recommended the penile pump .. The one i am working on i keep in the fridge . I know its largely unknown how or if and how much of any ED or incontinence one is likely to have based on your surgeon, anatomy, and how well you recover. Since my RRP in March, I've had no luck at all when it comes to recovering sexual function with regard to achieving erections. Would all the cancer be removed? Incontinence has not really been. In reading online, I noticed that, while the three components seem to always be the same, the amounts/concentrations are not and can be variable. Does anybody know if they can in fact be re-frozen? My father had radiation and is doing well. im 48 and was diagnosed 3plus4 7 gleason, no escape from the prostate. usually its at the end of day or when tired etc. Refrigerated, Trimix loses strength at about 1% per week. For a short, weekend trip, they are advised to draw up their syringe at about 1.25 times their normal dose and keep it at no more than room temperature (70F). He adjusted it to 5 and it was almost as painful and then he went down to 4, missed the site and freaked us out (nothing happened of course) and then we had success a couple times. Are you sure you want to block this member? My testosterone has returned to 300 so in the low normal range. The Case Against Coronary Artery Calcium Scoring for Cardiovascular Disease Risk Assessment. All lower left. You can tell no difference between the first shot and the last. My husband has been on Sildenafil 20 mg for almost a year since his Robotic prostatectomy. The doctor gave me this first shot so I assume the inje, I am wondering if any men have experienced an almost total lack of spousal support and intimacy following your prostate cancer diagnosis and subsequent robotic nerve sparing radical prostatectomy. This site uses cookies to help personalise content, tailor your experience and to keep you logged in if you register. He said he would start off with a low dose of .15 cc . Any advice. Gleason score of 6. Alprostadil lost 6% effectiveness under refrigeration after 30 days. As I'm a few weeks from my 80th birthday, there's no way I can use enough of it to make the cost per injection worthwhile. However, results are not optimum and resulting erecting is painful to the point that intercourses is not enjoyable. I keep it frozen all time ,I let melt draw a shot put Bach in freezer. Expert opinion suggests that ED sufferers need to get at least three erections a week. I knew t, i am almost four months post robotic surgery. I bought one of those pump things and it was simply ineffective and painful. Under refrigeration, it lost 6% potency after one month and 11% after two months. Frozen, alprostadil lost less than 5% after six months.. I had 5 of 12 cores positive. I was recently diagnosed. Alprostadil lost 44% effectiveness at room temperature after 30 days. I am a 46 year old male. Have questions about navigating your Inspire support community or need assistance from one of our Community Managers? undefined will no longer be visible to you including posts, replies, and photos. I intend to keep using the vial as long as it works. All treatment and consults at Mt Sinai in NY. 9/26/18: Over the past few weeks, it has been recommended to me by 3 dif, Hi At 70F (room temperature), alprostadil losts 10% effectiveness after 6 weeks. A brief history: If you do not refrigerate Trimix, prostraglandin, the third ingredient will slowly degrade. Stopped HCG, better libido and daily morning wood. I found a bottle way back in the Refrigerator that is 3 years old (per mix).. By any chance would that bottle still be at any use or good? this past January/18 for depression and regret at having had a prostatectomy and now no response, Been a month since leaving hospital and the fact that I had no nerve sparing the reality of ED is now hitting home. To be honest, I cannot imagine interc, Anyone ever experience a contraindication with any mixture used for injection therapy? So it would appear that those using Tri-mix could, when traveling, leave it. My oncologist says there is nothing to do at this point but keep checking every 4 months or so. Because of my husband's young age and his strong family history every doctor we have seen has recommended RP. i was thinking of stocking up. This was highly effective in producing an erection but i, Hi everyoneI need opinions.. 1 . Welcome to ExcelMale.com, the leading and best-moderated mens health forum focused on increasing health, potency and productivity in men. Now Im a 3+4 . Initially, I experienced a 9 out of 10 erection(4hr. Find other members in this community to connect with. Been using a pump for 3-4 months. ZERO - The End of Prostate Cancer Support Community. Can lowering cholesterol cause low testosterone? Been taking 2 tabs of Viagra daily. Dr felt it before the biopsy. thanks in advance to all that reply.. Now I'm getting two different recommendations from two different Urologists.. Alprostadil lost 12.5% effectiveness at room temperature after seven days. Stored in a syringe, alprostadil lost 10% effectiveness at 41F (refrigeration) after 24 weeks. Was told that maybe wi, 4 months after RP, working to improve ED problems. There are a lot of posts on the ED issues and the quality of an erection. At what Free T level do you feel optimal? 2. I'm about to start Trimix injections to solve a problem worsened by radiation treatments for prostate cancer. I keep them in there unrefrigerated until I run out. For that I am happy and, Like many men who have had treatment for Prostate Cancer, I have had ED as a side effect. What is one unexpected way a cancer diagnosis has impacted your life? I wo, Dear members, Inspire is dedicated to helping you connect with others and learn as you share stories. Also by prefilling the syringes it'd less intrusive on the moment. I very much like my orgasms and having a hard time with the no ejaculation thing. Alprostadil can be frozen for six months with 95% effectiveness. Going to give nebido another shot! This community is sponsored by ZERO - The End of Prostate Cancer, an Inspire trusted partner. Anyone use MUSE Urethral Suppositories in their rehab program? My father had prostate cancer 4 years ago at the age of 64. 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